Does Periodontal Treatment in Patients with Diabetes Lower Blood Sugar Levels?

May 13, 2010

The Cochrane Oral Health Group recently published Treatment of periodontal disease for glycaemic control in people with diabetes, a systematic review examining the relationship  between periodontal treatment and glycaemic control in diabetics.

The review, which included 7 Randomized Controlled Trials concluded there is evidence of improvement in metabolic control in people with diabetes, after treating periodontal disease.

For more detail, read the full review or listen to the podcast.

More resources may be found by browsing Bibby library’s selected  list of websites on diabetes and oral health.

A bibliography of meta-analysis, RCT’s and reviews follows:

Effect of periodontal treatment on glycemic control of diabetic patients: a systematic review and meta-analysis. Diabetes Care. 2010 Feb;33(2):421-7. Teeuw WJ, Gerdes VE, Loos BG.

Short-term effects of photodynamic therapy on periodontal status and glycemic control of patients with diabetes. J Periodontol. 2009 Oct;80(10):1568-73. Al-Zahrani MS, Bamshmous SO, Alhassani AA, Al-Sherbini MM.

Periodontal treatment to improve glycaemic control in diabetic patients: study protocol of the randomized, controlled DIAPERIO trial. Trials. 2009 Aug 2;10:65. Vergnes JN, Arrivé E, Gourdy P, Hanaire H, Rigalleau V, Gin H, Sédarat C, Dorignac G, Bou C, Sixou M, Nabet C.

Effectiveness of full-mouth and partial-mouth scaling and root planing in treating chronic periodontitis in subjects with type 2 diabetes. J Periodontol. 2009 Aug;80(8):1237-45. Santos VR, Lima JA, De Mendonça AC, Braz Maximo MB, Faveri M, Duarte PM.

The effect of periodontal therapy on serum TNF-alpha and HbA1c levels in type 2 diabetic patients. Dağ A, Firat ET, Arikan S, Kadiroğlu AK, Kaplan A.Aust Dent J. 2009 Mar;54(1):17-22.

Effect of antimicrobial periodontal treatment and maintenance on serum adiponectin in type 2 diabetes mellitus. Matsumoto S, Ogawa H, Soda S, Hirayama S, Amarasena N, Aizawa Y, Miyazaki H.J Clin Periodontol. 2009 Feb;36(2):142-8.

Relationship of Porphyromonas gingivalis with glycemic level in patients with type 2 diabetes following periodontal treatment. Oral Microbiol Immunol. 2008 Aug;23(4):348-51. Makiura N, Ojima M, Kou Y, Furuta N, Okahashi N, Shizukuishi S, Amano A.

Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study. J Clin Periodontol. 2007 Jan;34(1):46-52. Epub 2006 Nov 24. Jones JA, Miller DR, Wehler CJ, Rich SE, Krall-Kaye EA, McCoy LC, Christiansen CL, Rothendler JA, Garcia RI.

Does periodontal treatment improve glycemic control in diabetic patients? A meta-analysis of intervention studies. J Dent Res. 2005 Dec;84(12):1154-9. Janket SJ, Wightman A, Baird AE, Van Dyke TE, Jones JA.

Effect of non-surgical periodontal treatment with or without doxycycline on the periodontium of type 1 diabetic patients. Llambés F, Silvestre FJ, Hernández-Mijares A, Guiha R, Caffesse R.J Clin Periodontol. 2005 Aug;32(8):915-20.

The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus. Kiran M, Arpak N, Unsal E, Erdoğan MF.J Clin Periodontol. 2005 Mar;32(3):266-72.

Therapy with adjunctive doxycycline local delivery in patients with type 1 diabetes mellitus and periodontitis. Martorelli de Lima AF, Cury CC, Palioto DB, Duro AM, da Silva RC, Wolff LF.J Clin Periodontol. 2004 Aug;31(8):648-53.

The effects of periodontal treatment on diabetes. J Am Dent Assoc. 2003 Oct;134 Spec No:41S-48S.  Taylor GW.

Effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus. J Periodontol. 2003 Sep;74(9):1361-7. Rodrigues DC, Taba MJ, Novaes AB, Souza SL, Grisi MF.


Read Summaries of Systematic Reviews

March 25, 2010

Wouldn’t it be nice if you could find all the systematic reviews pertaining to dentistry in one place?  You can!

The American Dental Association (ADA)  Evidence Based Dentistry website includes a database of systematic reviews in oral health. The reviews may be found by searching the site or using the ADA’s drill down topic menu.

Even better, the ADA provides  critical summaries of many of these  systematic reviews.  Critical summaries are brief, concise assessments of a review that are written by ADA Evidence Reviewers.  These reviewers are trained  in the critical appraisal of scientific literature.

Here is a list of the most recently published critical summaries:


Does Treating Gum Disease Reduce the Incidence of Preterm Birth?

February 4, 2009

Previous research has suggested a link between periodontal disease and premature birth.  Consequently, pregnant woman have been encouraged to undergo periodontal treatment to reduce these risks.

However, recent studies conducted at the Univeristy of North Carolina’s School of Dentistry revealed no significant differences in pregnancy outcomes when study participants received treatment, as compared to those participants who did not.

As a result of these findings, the American Academy of Periodontology (AAP) released a statement calling for additional research to “clarify the potential impact that periodontal disease has on the risk of preterm births“.  The AAP also continues to encourage pregnant women to care for their oral health.

You  may also wish to read what the ADA has to say about this topic.

For information on current studies visit clinicaltrials.gov or browse this list of recent articles as indexed in PubMed.


Learn about the Link Between Heart Disease and Oral Health

January 27, 2009

February is American Heart Month.  What does this have to do with dentistry?  Come to find out, alot! Research suggests a significant link between oral and cardiovascular health.

In particular, periodontal health seems to play a major role.  Read what the American Academy of Periodontology has to say about periodontal disease and the heart.

You may also wish to browse this list of recent reviews pertaining to oral health and the heart:

Antibiotic prophylaxis for preventing endocarditis and infection in joint prosthesis after dental treatment: a review of new trends and recommendations in the literature. Kotze MJ. SADJ : journal of the South African Dental Association 2008 Sep;63(8):440-4. Review.

Antibiotics for the prophylaxis of bacterial endocarditis in dentistry. Oliver R, Roberts GJ, Hooper L, Worthington HV. “Cochrane database of systematic reviews . 2008 Oct 8;(4):CD003813. Review.

A change of heart: the new infective endocarditis prophylaxis guidelines. Daly CG, Currie BJ, Jeyasingham MS, Moulds RF, Smith JA, Strathmore NF, Street AC, Goss AN. Australian dental journal 2008 Sep;53(3):196-200; quiz 297. Review.

Cardiovascular disease and periodontitis: an update on the associations and risk. Persson GR, Persson RE. Journal of clinical periodontology. 2008 Sep;35(8 Suppl):362-79.

Inflammation, C-reactive protein, and atherothrombosis.  Ridker PM, Silvertown JD. Journal of periodontology 2008 Aug;79(8 s):1544-51.

Dental treatment, antibiotic cover and infective endocarditis: a major rethink. Seymour RA. Dental update. 2008 Jul-Aug;35(6):366-8, 370. Review.

The effect of chronic periodontitis on the development of atherosclerosis: review of the literature. Niedzielska I, Janic T, Cierpka S, Swietochowska E. Medical science monitor : international medical journal of experimental and clinical research. 2008 Jul;14(7):RA103-6.

The link between periodontal disease and cardiovascular disease is probably inflammation. Davé S, Van Dyke T. Oral Dis. 2008 Mar;14(2):95-101.

Associations between periodontal diseases and systemic diseases: a review of the inter-relationships and interactions with diabetes, respiratory diseases, cardiovascular diseases and osteoporosis. Kuo LC, Polson AM, Kang T. Public Health. 2008 Apr;122(4):417-33. Epub 2007 Oct 29.15.


Preterm Birth and Oral Health

November 17, 2008

The March of Dimes is celebrating Prematurity Awareness throughout the month of November. The goal of this event is to draw attention to premature birth, which affects more than 530,000 babies each year in the United States.

In the first of what will be an annual Premature Birth Report Card, the nation received a D and not a single state earned an A when the March of Dimes compared actual preterm birth rates to the national Healthy People 2010 objective.

Recent studies have linked maternal periodontal disease to preterm birth.  Furthermore, studies have indicated that the treatment of periodontitis in pregnant mothers can reduce the risk of preterm birth.

For additional information on premature birth and oral health, see this list of internet resources.


Diabetes, TMJ and November

October 31, 2008

November is American Diabetes Month and TMJ Awarness Month.  Here are some resources related to these topics.

Diabetes and Dentistry:

TMJ:


Oral Health: The Public Speaks

October 20, 2008

The American Dental Association, in collaboration with Crest and Oral-,B conducted a national public opinion survey on oral health care.  The survey represented  1,000 Americans ages 18 and older, living in the continental United States. The survey focused on the following areas:

  • The public’s perceptions of their oral health care, with a special focus on African Americans, Hispanics and lower-income Americans
  • Americans’ knowledge of effective and essential oral health care habits
  • Oral health habits among the nation’s youth
  • The psychological benefits of a healthy smile

Key findings include:

  • Eight out of  ten Americans say taking care of one’s mouth, teeth and gums is “absolutely needed; however, only one-third of them say they do an “excellent” job taking care of them
  • One out of four parents describe their children’s job of taking care of their oral health as fair” or “poor”

More than one in three Americans say:

  • They think a little bleeding from brushing is normal (33%)
  • They are unaware that periodontal disease needs to be treated and cannot be left alone (33%)
  • They don’t know that poor oral health has been associated with serious health conditions such as stroke, heart disease  and diabetes (37%)

The full report and related documents are available on the ADA site.

Links to resources for educating your patients on oral health conditions, treatment and prevention may be found here.


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