Does Periodontal Treatment in Patients with Diabetes Lower Blood Sugar Levels?

May 13, 2010

The Cochrane Oral Health Group recently published Treatment of periodontal disease for glycaemic control in people with diabetes, a systematic review examining the relationship  between periodontal treatment and glycaemic control in diabetics.

The review, which included 7 Randomized Controlled Trials concluded there is evidence of improvement in metabolic control in people with diabetes, after treating periodontal disease.

For more detail, read the full review or listen to the podcast.

More resources may be found by browsing Bibby library’s selected  list of websites on diabetes and oral health.

A bibliography of meta-analysis, RCT’s and reviews follows:

Effect of periodontal treatment on glycemic control of diabetic patients: a systematic review and meta-analysis. Diabetes Care. 2010 Feb;33(2):421-7. Teeuw WJ, Gerdes VE, Loos BG.

Short-term effects of photodynamic therapy on periodontal status and glycemic control of patients with diabetes. J Periodontol. 2009 Oct;80(10):1568-73. Al-Zahrani MS, Bamshmous SO, Alhassani AA, Al-Sherbini MM.

Periodontal treatment to improve glycaemic control in diabetic patients: study protocol of the randomized, controlled DIAPERIO trial. Trials. 2009 Aug 2;10:65. Vergnes JN, Arrivé E, Gourdy P, Hanaire H, Rigalleau V, Gin H, Sédarat C, Dorignac G, Bou C, Sixou M, Nabet C.

Effectiveness of full-mouth and partial-mouth scaling and root planing in treating chronic periodontitis in subjects with type 2 diabetes. J Periodontol. 2009 Aug;80(8):1237-45. Santos VR, Lima JA, De Mendonça AC, Braz Maximo MB, Faveri M, Duarte PM.

The effect of periodontal therapy on serum TNF-alpha and HbA1c levels in type 2 diabetic patients. Dağ A, Firat ET, Arikan S, Kadiroğlu AK, Kaplan A.Aust Dent J. 2009 Mar;54(1):17-22.

Effect of antimicrobial periodontal treatment and maintenance on serum adiponectin in type 2 diabetes mellitus. Matsumoto S, Ogawa H, Soda S, Hirayama S, Amarasena N, Aizawa Y, Miyazaki H.J Clin Periodontol. 2009 Feb;36(2):142-8.

Relationship of Porphyromonas gingivalis with glycemic level in patients with type 2 diabetes following periodontal treatment. Oral Microbiol Immunol. 2008 Aug;23(4):348-51. Makiura N, Ojima M, Kou Y, Furuta N, Okahashi N, Shizukuishi S, Amano A.

Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study. J Clin Periodontol. 2007 Jan;34(1):46-52. Epub 2006 Nov 24. Jones JA, Miller DR, Wehler CJ, Rich SE, Krall-Kaye EA, McCoy LC, Christiansen CL, Rothendler JA, Garcia RI.

Does periodontal treatment improve glycemic control in diabetic patients? A meta-analysis of intervention studies. J Dent Res. 2005 Dec;84(12):1154-9. Janket SJ, Wightman A, Baird AE, Van Dyke TE, Jones JA.

Effect of non-surgical periodontal treatment with or without doxycycline on the periodontium of type 1 diabetic patients. Llambés F, Silvestre FJ, Hernández-Mijares A, Guiha R, Caffesse R.J Clin Periodontol. 2005 Aug;32(8):915-20.

The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus. Kiran M, Arpak N, Unsal E, Erdoğan MF.J Clin Periodontol. 2005 Mar;32(3):266-72.

Therapy with adjunctive doxycycline local delivery in patients with type 1 diabetes mellitus and periodontitis. Martorelli de Lima AF, Cury CC, Palioto DB, Duro AM, da Silva RC, Wolff LF.J Clin Periodontol. 2004 Aug;31(8):648-53.

The effects of periodontal treatment on diabetes. J Am Dent Assoc. 2003 Oct;134 Spec No:41S-48S.  Taylor GW.

Effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus. J Periodontol. 2003 Sep;74(9):1361-7. Rodrigues DC, Taba MJ, Novaes AB, Souza SL, Grisi MF.

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Does Treating Gum Disease Reduce the Incidence of Preterm Birth?

February 4, 2009

Previous research has suggested a link between periodontal disease and premature birth.  Consequently, pregnant woman have been encouraged to undergo periodontal treatment to reduce these risks.

However, recent studies conducted at the Univeristy of North Carolina’s School of Dentistry revealed no significant differences in pregnancy outcomes when study participants received treatment, as compared to those participants who did not.

As a result of these findings, the American Academy of Periodontology (AAP) released a statement calling for additional research to “clarify the potential impact that periodontal disease has on the risk of preterm births“.  The AAP also continues to encourage pregnant women to care for their oral health.

You  may also wish to read what the ADA has to say about this topic.

For information on current studies visit clinicaltrials.gov or browse this list of recent articles as indexed in PubMed.


Top 10 Books @ Bibby Library

August 15, 2008

The following are the ten most popular books at Bibby library.  These are used the most frequently of all the books in our collection.  If you are a student, faculty or staff member of the University of Rochester, you can borrow them too!

10. Orthodontics and dentofacial orthopedics /  McNamara, Brudon, Kokich

9.   Carranza’s clinical periodontology

8.   Phillips’ science of dental materials

7.   Orthodontics : current principles and techniques / Graber,Vanarsdall

6.   Stewart’s clinical removable partial prosthodontics.

5.   Fundamentals of operative dentistry : a contemporary approach / Summitt, Robbins

4.   Principles and practice of implant dentistry / Weiss

3.   Contemporary orthodontics / Proffitt

2.   Essentials of facial growth / Enlow

1.   Periodontal surgery : a clinical atlas / Sato


Periodontitis/Diabetes Link

July 2, 2008

Evidence of the link between periodontal disease and diabetes continues to grow, as indicated in a recent article by Robert Finn of Elsevier’s Global Medical News. Diabetes appears to induce periodontal disease or cause it to worsen in some patients, but periodontal disease seems to worsen glycemic control.

Evidence to support this conclusion stems in part from the “Scottsdale Project”.  The project consisted of 18 physicians, dentists, and other independent experts who met in Scottsdale, Arizona in April 2007 to review the strength of evidence for associations among periodontitis, diabetes, and cardiovascular disease. Participants conducted a systematic review of 118 published articles in an attempt to answer eight focused questions. 

Other data comes from analyses of the third National Health and Nutrition Examination Survey.

Read the full article, which contains additional resources, here.

Information on the connection between periodontits and systemic diseases was also discussed in an earlier post on this blog.


Relationship Between Periodontal Disease and Chronic Diseases

June 17, 2008

The association between periodontal diseases and systemic conditions such as heart disease and stroke, and a higher risk of preterm low birth-weight babies, is garnering attention in the media. Similarly, recognition of the threats posed by periodontal diseases to patients with chronic diseases such as diabetes, respiratory diseases and osteoporosis is acknowledged.

The following are some links to recent stories and resources on these topics:


Periodontal Disease and Systemic Health

April 30, 2008

In January of 2008, the New York Academy of Science (NYAC) hosted From Basic Science to Clinical Practice and Policy: A Medical-Dental Dialogue on the Relationship between Periodontal Disease and Systemic Health.  The event was a continuing medical education activity also organized by the College of Physicians & Surgeons, Columbia University, and the National Periodontal Disease Coalition.

A full report of the meeting may be read here.

Presentations from this conference may be viewed by selecting the title on this page.  Topics include periodontits and vascular disease, preterm birth, kidney disease, renal disease and more.

NYAC has also provided an overview, meeting abstracts, information on the presenters, and other resources as part of it’s e-briefing.


Cannabis Smoking Increases Risk of Periodontal Disease

April 11, 2008

Tobacco smoking has been a known risk factor for periodontitis but it was uncertain whether or not cannabis use was harmful.  Essential Evidence Plus reviews a recent cohort study, published in the Journal of the American Medical Association, which concluded that regular marijuana smoking increases the risk of periodontal disease and subsequent loss of teeth.

Read the full review here.

A list of additional articles on this topic may be found in PubMed.


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